刘振,博士,36365路检测中心副研究员,硕士士生导师。天津市“131”创新型人才培养工程第三层次,天津市高校“青年后备人才支持计划”。
主讲课程
本科生:《免疫学》、《制药工艺实验》
研究生:《科技论文写作》
科研领域及方向
[1] 抗肿瘤药物药理作用研究
[2] 功能性保健品研发
科研项目情况
[1] 国家自然科学基金青年科学基金项目,81703014,2018/01-2020/12,主持
[2] 天津市教委科研计划项目,2017KJ010,2017/05-2020/04,主持
[3] 中国博士后科学基金面上项目,2015M570229,2015-2016,主持
[4] 国家自然科学基金面上项目,81673647,2017/01-2020/12,第二主持人
[5] 国家自然科学基金青年科学基金项目,31601203,2017/01-2019/12,第二主持人
[6] 4,4 '-二取代查尔酮吡唑及其衍生物的合成及功效研究,横向,2019/04-2019/06,主持
[7] 新型查尔酮衍生物治疗非酒精性脂肪肝炎的研究与应用,横向,2019/06-2019/12,主持
[8] 喜树碱化合物对内皮细胞及癌细胞的生物活性研究,横向,2019/07-2019/10,主持
主要学术成果
以第一作者/通讯作者发表科研论文20篇,近五年发表的主要学术论文有:
[1] Liu Z*, Xu Y, Guo LQ, Li XR, Gao JL, Xie WR, Zhao LB, Teng YO, Li XJ*, Yu P*. Development of 10-Hydroxycamptothecin-crizotinib conjugate based on the synergistic effect on lung cancer cells. Journal of Enzyme Inhibition and Medicinal Chemistry, 2023, 38(1):1-11
[2] Liu Z*, Li XR, Gao JL, Yin PP, Teng YO, Yu P*. The therapeutic inhibition of topoisomerase inhibitor and crizotinib combination in EGFR wild and mutant lung cancer cells. Biochemical Pharmacology, 2022, 205: 115294
[3] Liu Z*, Xu Y, Bai XM, Guo LQ, Li XR, Gao JL, Teng YO*, Yu P*. Prediction of the mechanisms of action of Zhibai Dihaung Granule in cisplatin-induced acute kidney injury: A network pharmacology study and experimental validation. Journal of Ethnopharmacology, 2022, 292: 115241
[4] Liu Z*, Guo LQ, Yin PP, Zhang F, Song WJ, Gao JL, Li XR, Teng YO, Yu P*. Topotecan inhibits metastasis of non-small cell lung cancer by regulating epithelial-mesenchymal transition. European Journal of Medicinal Chemistry Reports, 2022, 5: 100051
[5] Liu Z*, Fu QS, Wang Y, Cui L, Zhang WQ, Teng YO*, Yu P*. Synergy between vinorelbine and afatinib in the inhibition of non-small cell lung cancer progression by EGFR and p53 signaling pathways. Biomedicine & Pharmacotherapy, 2021, 134:111144
[6] Liu HY, Fu QS, Lu Y, Zhang WQ, Yu P, Liu Z*, Sun XS. Anti-tubulin agent vinorelbine inhibits metastasis of cancer cells by regulating epithelial-mesenchymal transition European Journal of Medicinal Chemistry, 2020, 200: 112332.
联系方式
办公地点:天津经济技术开发区第十三大街9号36365路检测中心
邮政编码:300457
手机号:13820065957
办公电话:022-60912562
Email:liuzhen5957@tust.edu.cn